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Understanding Side Effects of HRT Patches: Evorel Guide

This article provides an in-depth look at the side effects associated with hormone replacement therapy (HRT) patches, specifically Evorel, offering essential information for individuals considering or currently using these treatments. Note - side effects apply to all brands of HRT patches - including also Estradot, Femseven and Estraderm.

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Common Side Effects of Evorel Patches

While Evorel patches can be highly beneficial, they do carry potential side effects. Common issues include:

  • Skin irritation at the site of application, typically presenting as redness, itching, or rashes.
  • Headaches, which often improve as the body adjusts to the treatment.
  • Breast tenderness or enlargement, a common response to oestrogen therapy.
  • Gastrointestinal disturbances, such as nausea or abdominal pain.
  • Fluid retention
  • Psychological symptoms including low mood and anxiety

These side effects are generally mild and diminish over time.

Less Common and Serious Side Effects

While most individuals tolerate treatments without major issues, a small percentage may encounter less frequent yet significant side effects. Some risks only apply to oral HRT and NOT to Evorel patches. They are included here for context.

  • Venous thromboembolism (VTE), or blood clots, poses a severe risk and can be fatal if not treated promptly. The risk of VTE increases above baseline when oestrogen is swallowed in oral preparations, but this risk does not increase when Evorel products are used in standard doses.
  • Stroke and heart attack risk may increase when oral HRT is taken.
  • Endometrial hyperplasia, a condition characterised by an abnormal increase in the lining of the uterus, potentially leading to cancer if left unchecked. This is a risk for those taken oestrogen only HRT, including patches, when they have a womb. It is important to take a progestogen alongside the oestrogen if the womb is intact – ie no hysterectomy. This is also a risk when sequential (or cyclical) HRT is taken for more than 5 years. See here for more information.
  • Gallbladder disease is a risk that is greater with oral HRT compared with transdermal HRT (patches, gels or spray.)
  • Breast cancer risk increases with duration of HRT use. Route of delivery does not make a difference to the risk. Oestrogen only HRT (following hysterectomy) has a lower risk of breast cancer than combined HRT, but the risk is still very low in absolute numbers.

Factors Influencing Side Effects

The likelihood and severity of side effects arising from the use of Evorel patches can be influenced by various factors. Being aware of these can help in managing and reducing the potential risks associated with hormone replacement therapy (HRT) patches:

  • Age and overall health status play a role. Older adults, who may need lower doses of oestrogen to help manage symptoms, or those with existing health conditions may experience more pronounced side effects.
  • Concurrent medications can also affect the body’s response to Evorel patches. Certain drugs which slow the metabolism of hormones might interact with the hormonal components may exacerbate side effects. Other drugs which speed up the metabolism of hormones may decrease HRT effectiveness. See here to check any interaction of any medication you may be taking already.
  • Duration and dosage of the therapy are significant as well. Generally, higher doses and prolonged use may elevate the likelihood of encountering adverse effects.

By understanding and considering these factors, individuals using HRT patches can better manage their treatment and minimise potential side effects.

Managing and Reducing Side Effects

To manage and potentially reduce the side effects associated with Evorel patches:

  • Regular monitoring by a healthcare provider is essential.
  • Adjusting the dose or switching to a different type of HRT can be effective.
  • Maintaining a healthy lifestyle, including a balanced diet and regular exercise, supports overall well-being and can alleviate some symptoms.

 

Alternative Treatments to HRT Patches

If Evorel patches are not suitable, other HRT forms or alternative treatments may be considered:

  • Oral HRT, which involves daily tablets.
  • Gels or sprays that are applied directly to the skin.
  • Non-hormonal treatments, such as herbal remedies or lifestyle adjustments, can also be effective for some women.

Each alternative has its own benefits and potential side effects, and a healthcare provider can offer guidance based on individual health needs.

Conclusion: Consulting with a Healthcare Provider

In the UK, managing menopausal symptoms with hormone replacement therapy (HRT), such as Evorel patches, can markedly enhance one’s quality of life. However, it is important to acknowledge that these treatments do carry potential side effects. Therefore, it is absolutely vital to consult with a healthcare professional who can customise the treatment according to individual requirements and health circumstances. Engaging in regular consultations allows for the monitoring and adjustment of the therapy, ensuring it remains both safe and effective for the patient. This personalised approach helps mitigate risks and maximises the therapeutic benefits of HRT, making it a critical step for those considering this form of treatment.

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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